PAST TREATMENT: Per chart review, past treatments for lymphedema have included H2O2, Polysporin ointment, Domeboro's Solution, lymphedema pumps, and compression stockings. Compression wraps were the current treatment.
ANGIOSARCOMA in LONG TERM LYMPHEDEMA : Angiosarcoma is a rare vascular malignancy, accounting for less than 1% of all sarcomas. Angiosarcoma that arises in an area of chronic lymphedema is known as Stewart-Treves syndrome. The prognosis is poor.
TREATMENT: After consultation with oncology, it was decided to proceed with a left above the knee amputation.
PATIENT OUTCOMES: A left above knee amputation performed in May 2005. The patient tolerated surgery well.
CONCLUSION: Although rare, angiosarcoma can occur in patients with long standing lymphedema. CLINICAL IMPLICATIONS: Patients with chronic lymphedema must be monitored for any atypical lesion, which should be promptly biopsied. LIMITATIONS: There is limited awareness of lymphedema treatment in general, with many patients untreated for years.
FINANCIAL ASSISTANCE/DISCLOSURE: No financial assistance was received for this study
REFERENCES: Breidendbach, M; Rein, D; Schmidt, T; Heindel, W; Kolhagen,H; Mallmann, P; Kurbacher, C M. Intra-arterial mitoxantrone and paclitaxel in a patient with Stewart-Treves syndrome:selection of chemotherapy by an ex vivo ATP-based chemosensitivity assay Anti-Cancer Drugs. 2000; Volume 11 (4): 269-273
Komorowski, Andrzej; Wysocki, Wojciech; Mitus, Jerzy. Angiosarcoma in a Chronically Lymphedematous Leg: An Unusual Presentation of Stewart-Treves Syndrome. The Southern Medical Journal 2003; Volume 96 (8) 807-808
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