CLINICAL PROBLEM: Skin protectant barriers are an essential component of a well structured perineal skin care plan throughout the continuum of care for all ages (neonates – geriatrics). Often perineal skin injury is associated with considerable pain and can be complicated with the presence of candidiasis. Numerous skin protectant barriers exist with varying degrees of aesthetics and effectiveness. Some products are transparent (barrier films) but do not adhere well with skin erosion and are incompatible with other commonly used skin care products. Other products adhere well with erosion (zinc oxide pastes), but are opaque and often prematurely removed to monitor the skin. This in not only uneconomical, but can also harm the skin and cause considerable discomfort to the patient, which can diminish quality of life. Furthermore, the use of multiple, and sometimes incompatible, products at patient bedside can be confusing to caregivers. DESCRIPTION OF PAST MANAGEMENT: Typically, barrier ointments and creams are used for preventative care, while zinc oxide pastes are used when erosion is present. Antifungal products are implemented when candidiasis is present. CURRENT CLINICAL APPROACH: Case studies are presented that demonstrate the clinical utility of a new family of non-greasy, preservative free, detectably transparent, non-transferring, petrolatum based skin protectant barriers. These products are both effective and adhere well to damaged skin. They are designed to relieve erythema, erosion, candidiasis and pain. PATIENT OUTCOMES: Patients were followed for a minimum of three days, and all showed considerable resolution of erythema, erosion, candidiasis and pain. CONCLUSION: This new family of non-greasy, preservative free, detectable transparent, non-transferring, petrolatum based skin protectant barriers, was easy to use, completely compatible with each other, showed excellent clinical outcomes, and decreased the number of products at patient bedside. * Sween® Critic-Aid® Clear, Critic-Aid® Clear AF