The purpose of this study was to evaluate the rheological properties of several skin protectant formulations. Rheology is the science of the deformation and flow of materials in terms of stress‚ strain‚ and time. In this study‚ oscillation and flow experiments were conducted to determine the rheological profiles of several formulations. In use‚ these profiles give insight into key aspects of the utility of a given formulation such as “spreadability”, structural integrity (stability), and shelf life. The “spreadability” gives an indication of how easily the formulation will spread on the skin and how well it will be absorbed into the skin delivering its therapeutic agents. Stability gives insight into the shelf life and efficacy over time. Stability of an emulsion is key to the shelf life and performance of the product. In this study a CarriMed-controlled stress rheometer, a cone and plate geometry (55 µm truncation) as used. With this instrument it was possible to gain accurate, repeatable data for both oscillation and flow experiments. To further evaluate the rigor of the rheological evaluations, the stability of the formulations in the presence of fluid was evaluated. The data indicated that there was a link between the rheological profiles and the stability in contact with fluid. Formulations with a higher level of structure (determined rheologically) were better able to maintain their structure in the presence of fluid. This finding provides more insight into rheology as a predictive tool of in use behavior of the formulations evaluated.