Purpose:  To standardize care in the Burn Intensive Care Unit at The Johns Hopkins Bayview Medical Center (JHBMC) using evidenced based practices which would ensure quality care and positive patient outcomes.  Description: In July, 2004 the Burn team identified a number of patient safety issues specific to the unit.  A Safety Attitude Questionnaire (SAQ) was administered to the multidisciplinary staff including the physician team.  Results from the questionnaire identified a number of opportunities for improving the safety culture in the unit. These improvements included a need to improve communication among the team, to standardize practice in the Burn Unit using evidenced based protocols, and to implement measures focusing on reducing infections. After the initial meetings, the team: developed and implemented a daily patient-specific goal sheet for use by all members of the healthcare team, appointed a Nurse Safety Officer, adopted a process of having twice daily multi-disciplinary care rounds for all patients in the Burn Center as a means of improving communication, implemented a Protocol Committee to address evidence based practices to be standardized in the Burn Center, completed, adopted, and implemented twenty-six different protocols for the care provided in the Burn Center.  Evaluation: After the items listed above were implemented the SAQ was re-administered to determine if the actions impacted safety in the unit. Results:  The increase in scores on the SAQ post implementation of the above measures was statistically significant. Staff agreement with physician and nurse collaboration increased from 57% to 92%.  Comfort in reporting safety concerns increased from 71% to 89%.  Staff satisfaction regarding patient care in the unit increased from 70% to 88%.  Staff morale is at an all time high from 35% in 2004 to 83% in 2006.