A new micro-adherent absorbent dressing is composed of a non-occlusive, micro-adherent lipidocolloid mass used in contact with the wound and the surrounding skin. The micro-adherence of this lipidocolloid mass to the wound bed, and skin around the wound is designed to make wound care easier for clinicians and thereby optimizing the management of chronic wounds.The authors will report the results of a prospective, non-comparative, multicenter clinical trial conducted on the local care of exuding venous leg ulcers during the granulation phase of healing. The 45 patients included in this clinical trial were followed-up by the investigating physicians every week for six weeks (clinical assessment, planimetric and photographic records) and by paramedical staff at each dressing change (nursing care record). After 6 weeks of treatment, the mean surface reduction was 37.4% compared to the baseline, tolerance was very good (3 local adverse events), the total treatment days were 1743 and acceptability (patient and paramedical parameters) will be reported and discussed. The observed results demonstrate the efficacy and tolerance of the lipidocolloid micro-adherent absorbent dressing in the treatment of venous leg ulcers. The better acceptability of this micro-adherent dressing justified substitution of the previous lipidocolloid foam with this new dressing, and is now available to health professionals.