Effectiveness of thopical innovation formula containing Zinc Oxide and Metronidazole for Malignant Fungating Wound, exudate and maloudor control in Dharmais Cancer Centre Hospital Indonesia

EFFECTIVENESS OF TOPICAL  INNOVATION FORMULA CONTAINING ZINC OXIDE  AND METRONIDAZOLE FOR  MALIGNANT  FUNGATING   WOUND  ODOR  AND  EXUDATE CONTROL, IN DHARMAIS   CANCER CENTRE HOSPITAL              JAKARTA-INDONESIA
Introduction :
In Indonesia especially in Dharmais Cancer Centre Hospital more than 60% patients came with advance  stage of cancer. And over than  10% of  patients have cancerous infiltration to the epithelium and became fungating wound. Fungating wound resulting in aprotrudity nodular and often grotesque growth which is prone to infection, bleeding and maloudor exudate (Foltz 1980, Fitzgerald & Sims, 1985). Beside that physical problems, patients also have psychological problems such as disturbance of body image and social isolation.
A holistic approach need to be done to solve all these problems. Colaborations of the ET nurse with the other health profider such as physicians, dietarians, pharmacist and patients also the family should be consider to have comprehensive treatment.
The Aim
This study reports upon study aimed to examine the effectiveness of topical  innovation formula’s to reduce maloudor and exudate of the fungating wound, and determine patient’s satisfactions.
Method
The Study was a prospective study ( uncontrolled trial) 118 respondent  presenting with malodorous wounds were enrolled for this clinical study during January – December 2008 period. All patients recieved  treatment witih the innovation topical formulation . Wound was evaluated  before and after initial application by patient and investigator. The patient were followed for 2 weeks..

Statistical Analysis :

The mean baseline scores were compared (pretest) to mean score following  treatment with topical innovation formulation (pos test), using a nonparametric test ( Friedman”s Test) for the comparison of repeated measures.

Results
Comparations result of the quisioner pre and post intervention of the patient using topical innovation  formula application are quite significant, patient who reports psychological problems like social isolation is reduce from 70% to 23%. Complete elimination of odor was reported in 79 patient (66,4%) before using the formula reduce to 33.6% after the application. Exudates control also reduce from 80% to 10% of the patients. Cost ability of the patient rise from 22% to 72% , e.uivalent to the patient satisfaction which is 57% rise to 84%.
Conclusion
According to the study result, the topical innovation formula is provent effective,  not only to reduce the maloudor and exudates, but also can rise the patient’s cost ability and satisfaction.
Keywords : Fungating wound, zinc oxide, metronidazole, maloudor and exudate.