The Adjunctive Use of Collagen/Oxidized Regenerated Cellulose Dressing in Complex Wounds

The use of a collagen/oxidized regenerated cellulose (ORC) dressing in a series of complex wounds is presented. Case 1, an 89-year-old male with a history of diabetes mellitus, peripheral vascular disease, and chronic obstructive pulmonary disease, presented with a traumatic wound on the dorsal anterior of the left great toe present for 7 days. The wound was debrided and covered with a collagen/ORC dressing and a silver finger/toe dressing. After 5 weeks, the wound was fully closed. Case 2, a 42-year-old male with a history of obesity and spina bifida, presented with a pressure ulcer on the right ischial tuberosity present for several weeks. Following debridement, the wound was covered with a collagen/ORC dressing and a secondary foam dressing. The wound closed within 21 days. Case 3 was a 75-year-old male with a history of alcohol use, diabetes mellitus, coronary heart disease, peripheral vascular disease (PVD), and hypertension. He presented with a venous leg ulcer on the posterior lower left leg present for 17 days. The wound was debrided and covered with a collagen/ORC dressing, non-adhesive silver foam dressing, and a 4-layer compression wrap. The wound healed within 17 days. Case 4 was a 93-year-old male with a history of coronary heart disease, PVD, hyperlipidemia, atrial fibrillation, peripheral arterial disease, mitral valve insufficiency, osteoarthritis, congestive heart failure, and second and third metatarsal amputation. He presented with a chronic ulcer present for 8 months on the right lateral foot near the fifth metatarsal and osteomyelitis. The patient was treated with intravenous and oral antibiotics, debridement, and application of a collagen/ORC dressing and negative pressure wound therapy. After 1 month, treatment was changed to a collagen/ORC dressing, silver hydrofiber dressing, and gauze wrap. The adjunctive treatment with a collagen/ORC dressing resulted in wound healing in 3 out of 4 cases.