Application of oxidized regenerated cellulose (ORC)/collagen/silver-ORC dressings to exuding wounds is reported to positively affect overall healing. We present cases using this advanced wound dressing in complex wounds. Patient 1 was an 89-year-old male with a history of pre-cancerous skin lesions who underwent surgical removal of melanoma from his elbow requiring a split-thickness skin graft from his thigh. No pain was reported due to little sensation in his thigh. Because of the amount of exudate, the donor site wound was cleaned, and an ORC/collagen/silver-ORC dressing was applied, followed by a non-adhering silicone dressing. After 2 weeks, most of the wound had closed. Patient 2 was a 71-year-old female who sustained a second degree burn with 2 small full-thickness wounds on her lower back and reported a pain level of 9/10. ORC/collagen/silver-ORC dressings were applied and covered with a silver cloth wrap. After 5 days, the larger burn area had completely epithelialized, but ORC/collagen/silver-ORC dressings continued to be used over other areas. On treatment day 12, the injury was assessed as two smaller full-thickness wounds with slough; patient reported a pain level of 0. ORC/collagen/silver-ORC dressings were reapplied and the remaining slough was removed with debridement 1 week later. Wounds continued to heal. Patient 3 was a 37-year-old female with diabetes who suffered a second degree burn on her leg and reported a pain level of 7/10. Wound was covered with ORC/collagen/silver-ORC dressings and a single-layer compression wrap. After 5 days, dressings were removed for debridement, with a pain level of 3/10. Dressings were reapplied. On day 12, wound was mostly closed and epithelialized. Treatment was switched to a topical skin protectant cream and compression wrap; full closure was achieved 1 week later. In these cases, use of ORC/collagen/silver-ORC dressings and secondary dressings and wraps resulted in positive outcomes.
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