The study aimed to identify and to analyze the prevalence of constipation and sociodemographic and clinical variables associated with their occurrence in hospitalized patients. This is an observational, cross-sectional, analytical and descriptive epidemiological study, where the study sample consisted of 345 adult and elderly patients hospitalized at a University Hospital. The data were collected through interviews, physical examination and medical records. The prevalence was obtained in a single day in four consecutive months (point-prevalence).This study considered as constipated the patients who met two or more Rome III Criteria. Data were analyzed using chi-square and Fisher tests for categorical variables, t-student and Mann-Whitney tests for numerical variables, and logistic regression for the identification of associated factors. P<0.05 was used for statistical significance, except for regression analysis variables insertion (p<0.1); 95% Confidence Interval was also analyzed.Results: the sample was characterized by women (194 / 56.3%) and Caucasians (165 / 47.8%); mean age of 48.9 years (SD = 21.2). The constipation prevalence was 14.9% (51/ 345), 15% (29/345) for women and 14.7% (22/ 345) for men. Among the constipated patients, 19 (37.3%) reported that the problem had started during hospitalization. There were statistically significant differences between the groups with and without constipation for the following variables: study years (p=0.028), diarrhea (p<0.001) and pelvic or abdominal radiotherapy (p<0.001). For women, there was no statistically significant difference between the groups with and without constipation for any variable, while for men, the only variable that emerged with a statistically significant difference between the groups with and without constipation was sexual impotence (p<0.001) .In the regression model, the variables that appeared associated with constipation were: years of study and use of laxatives.