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4438 New Skin Care Element (Ceramide) for Peri-stomal Skin Ulcer with IBD

Satoru Numata, BA , Medical Engineering Lab., ALCARE Co., Ltd., Senior reasearch fellow, Tokyo, Japan
Tetsuji Iwasaki, MS , Medical Engineering Lab., ALCARE Co., Ltd., Managing Executive Officer, Tokyo, Japan
Katsuhisa Shindo, MD, PhD , Kinki Univ. School of Med. Sakai Hospital, Professor, Osaka, Japan
PURPOSE: Ileostomy with IBD makes often the skin trouble that is not controlled by a dermatologist or an ET. Ceramide involved in the skin barrier is to be evaluated for the treatment of peristomal ulcer.

METHODS: Fundamental skin tested in two IBD cases with ulcerated peristomal skin of several years history: We measured Trans-epidermal water loss (TEWL) by AS-VT100 (ASAHI BIOMED), and Macro/derma scopic inspection, before.

RESULTS:

(1) The conventional skin barrier made ulcer both cases. All peristomal skin ulcers healed completely with ceramide quickly.

(2) Ceramide put TEWL decreased value in two cases tested skin.

CONCLUSIONS: Ceramide is effective for the treatment of peristomal ulcer by keeping TEWL lower due to maintaining intercellular lipids enough.

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